hmmm...human health state is getting worse nowadays...due to DNA mutations, tumour growths are induced....hopefully some anti tumour protein can be generated to cure cancer...and that would be a miracle...for your information, a potent cytotoxin known as BS-RNase had been developed and it's currently undergoing clinical trial (phase 1 & 2)to CURE cancer....however, it causes some side effects....(eg: degeneration of testicular tissues, affect embryonic growth as well as the maturation of oocyte)....
so, here come my research...recently, i had found out that a potential cytotoxin, lactoribonuclease, had been isolated. It has similar molecular weight and N-terminal amino acid protein as BP-RNase....So, the experiment i'll design is to engineer the protein into dimer, trimer and possibly tetramer form...(rational? BS-RNase (dimer) active, but non-specific cytotoxin, BP-RNase (monomer) lower cytotoxin activity, but more specific).....so, i'll just engineer the protein structure and test its activity....
i can only propose this research, but not to conduct it due to Human Tissue Act and i am not yet a biotechnologist...MOREOVER, i had tonnes of assignments waiting for me...
currently, i am also doing research on production of antibodies from plants and animals (eg: anti-S, insulin, hepatits B)...it's all possible~~
ps: i am actually praying that my coursemates wont be calling me up in the middle of the night again....i really need some time off!!
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It sounds complicated but interesting! Haha! Sigh~~~ I miss Bio so much!
miss BIO? ugh...i dont...but i prefer bio more than chem for sure! hahahhah! it's really interesting!
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